Evidence-Based Healing

Microdacyn leads the way in evidence-based care.

 

 

Super-oxidised solutions have some of the strongest evidence available that their use within a comprehensive treatment regime results in more effective infection control, faster healing rates, reduced time to wound healing all with unrivalled compatibility and tolerance.

 

 

If you practice evidence-based care,

welcome to Microdacyn

This page contains summaries and collections of the most relevant and up to date clinical support, guidelines and expert recommendations for Microdacyn as the leading surgical and wound management solution.

Bongio 2016 Cover.png
Armstrong Expert Recomm Cover 2015.png
IWII 2016 Cover.png
SOS WOUNDS 2006.png

Click The Cover If You Want To Download The Full Article

Review 2018: Consensus on Wound Antisepsis

In early 2018, Kramer et al published an updated consensus on wound antisepsis in the journal of skin pharmacology and physiology

The article independently collected all the quality clinical evidence produced by a PubMed literature search and tabulated the outcomes for various wound and surgical preparations including super-oxidised solutions.

 

Below is the extract data for Microdacyn where it was proven superior in wound healing or infection control (or both) in all trials against all comparators.

Summary: eight (8) controlled trials were quoted, six (6) were against Povidone-Iodine in wounds, one (1) was against saline in wounds and another one (1) was against saline in surgical irrigation of the peritoneum.
 

Additionally, the consensus included one retrospective cohort study against silver (Ag) in burn wounds.

Microdacyn significantly improved wound healing rates in all wound trials and significantly improved surgical recovery measures in the irrigation RCT

Consensus Cover 2018.png

Click To Download in Full

Recommendation:

Microdacyn is the 1st choice antiseptic compound for decontaminating acute and chronic wounds

If This Isn't Enough To Change Your Evidence-Based Practice, Nothing Will

Microdacyn Technology - Heals Like Nothing Else

Prevention is always better than treatment, however, in wound care that has always been a difficult task as antiseptic use to manage infection has not been without consequence.

Until  Microdacyn.

Each category will guide you to a clinical example where Microdacyn is proven to excel against the current standard of treatment

Cytotoxicity

Traditionally antiseptics have been high concentration active solutions that can cause harm to the delicate cells involved in wound healing that cause pain or allergy on application. Not Microdacyn.

 

The international Wound Infection Institutes (IWII) 2016 clinical practice guidelines clearly explain that lower-concentration products are less likely to cause harm to wound healing and are preffered.

In following with guideline recommendations, Microdacyn would be recommended ahead of its higher concentration comparators first line in all wound management 

Indicated Use of Microdacyn - Unrestricted

Due to the unique non-cytotoxic action used by super-oxidised solutions, Microdacyn is one of the only antimicrobial solution technologies indicated for even the most delicate human anatomy including; cartilage, CNS tissue and the peritoneum 

 

This makes Microdacyn an ideal surgical irrigation as well as topical technology

Microdacyn = 0.004% HOCl Super-oxidised solution

OCT = Octenidine dihydrochloride

PMHB = Polyhexanide

PVP-I - Povidone-Ioidne

 

Advanced Antisepsis, Non-Damaging To Healing

Infection, the most important complication relating to a wounds ability to heal.
Forming the foundation for Microdacyn's superior wound management is a technology that is clinically proven as a more potent antimicrobial when compared to powerful clinical standards such as 10% Povidone Iodine

Not only is Microdacyn less toxic to the wound but its more potent as an antimicrobial

Microdacyn was compared to Betadine in a randomized control trial measuring SSI (surgical site infection) rates.

178 patients undergoing coronary artery bypass grafting (CABG) were randomly selected to receive either Microdacyn or Betadine treatment for the surgical sites where the sternal wires were placed during cardiothoracic surgery 

  • The Microdacyn group incurred nearly half the superficial infections than that of the Betadine group (5.7% Vs 11.1% respectively)

    These superficial infections were managed with routine wound care and antibiotics

     

  • The Microdacyn group incurred no deep tissue infections compared to the 4 patients (4.4%) in the Betadine group that required surgical intervention and extended hospital resources to resolve

Abdul Mohd et al - Microdacyn Irrigation in Reducing Infection of a Median sternotomy Wound

The Heart Surgery Forum 13(4) 2010 DOI: 10.1532/HSF98.20091162 

 

Tissue Oxygenation

Many of the highly oxidising components that give Microdacyn is super-oxidising abilities are the same as those produced and consumed within our natural oxygen-dependent immune response. Principally hypochlorous acid (HOCl).

 

Oxygen is a crucial component of all life on earth and without it, no healing could occur.

Choosing a technology that utilises similar oxygen-derived molecules to those produced by the immune system may help us leverage the multiple roles they play in timely wound healing.

The use of Microdacyn in wounds such as diabetic and venous ulcers has demonstrated a rapid elevation in tcpO2 (transcutaneous oxygen pressure) for up to 72 hours per application

Right - Non-Insulin Dependent Diabetics (NIDDM) Cohort tcpO2 measures graphed from the below table (n=393)

Below - A table extract from a paper titled "Effects of Microdacyn Solution on Venous Leg Ulcers (VLU): Experience With 1249 VLUs in 897 Patients"

IDDM: Insulin Dependent Diabetes Mellitus, NIDDM: Noninsulin Dependent Diabetes Mellitus, BMI: Body Mass Index, PAD: Peripheral Artery Disease (Ankle/Brachial systolic pressure index <0.80), MDRI: Multidrug resistant infection

Cheryl M. Bongiovanni,  - PhD, RVT, CWS, FASA, FACCWS

Journal of the American College of Clinical Wound Specialists (2016) 6, 32–7

DOI: 10.1016/j.jccw.2016.01.001

 

Effect on Biofilm

The latest clinical practice guidelines published by the international wound infection institute cite super-oxidized hypochlorous acid (Microdacyn) with the ability to "penetrate biofilms rapidly, killing formations from within"

 

Further research inlcuding some of what is listed below confirm the onset of this action in minutes

IWII 2016 Cover.png

More research by Johani et al in 2017 discovered that only three of their test products were able to effect a statistically significant reduction of both gram negative and gram positive biofilms at 15 minutes;
 

  • Microdacyn SOS

  • Povidone-Iodine
    & Chlorhexidine

 

Summary & Action

As the literature for Microdacyn's efficacy in improved wound healing continues to grow the case for superiority is becoming somewhat irrefutable. With antibiotic resistance continuing to rise at an alarming rate the need to adopt these modern technologies is now!

 

If you're looking to adopt an evidence-based care model that improves healing and betters infection control outcomes then its time to make the switch to Microdacyn Wound Care

1800 83 2724

enquiries@tearaibiofarma.com

www.tearabiofarma.com.au

Auckland, NZ | Melbourne AUS

  • Facebook - Grey Circle
  • Instagram - Te Arai BioFarma
  • LinkedIn - Te Arai BioFarma
  • YouTube - Te Arai BioFarma

All Rights Reserved By Te Arai BioFarma